Following a Natural Sciences degree at Jesus College, University of Cambridge (1993-1996), Nick pursued a Ph.D. with Janet Thornton at UCL (1996-2000) on the basis for specificity of DNA-binding proteins. He moved to Yale University as an Anna Fuller Postdoctoral Fellow with Mark Gerstein (2000-2005), where he shifted to genomics with an emphasis on transcriptional regulation in yeast. He was Group Leader at the EMBL-European Bioinformatics Institute (2005-2012) in Cambridge and built a computational biology laboratory focused on genomics and gene regulation. During this time, he joined the Okinawa Institute of Science & Technology Graduate University as an Adjunct Faculty member to establish a small lab examining developmental regulation (2011-present). He returned to UCL as Chair in Computational Biology and holds a joint appointment as Winton Group Leader at the Francis Crick Institute (2012-present). Nick was elected EMBO member in 2013.